Guests will find the Hotel Irini ideally situated for business or pleasure. The hotel is located in a quiet area, but is also near the center of the city as well as the harbor. Guests of the hotel will have easy access to all of the popular attractions, including the Venetian Walls and the Archaeological Museum. There are also many restaurants and shops in the local area near the hotel. A car park is located at the Hotel Irini for the use of guests with cars. The airport is located within just a short drive of the hotel property. Public transportation services are offered in the local area.

The Hotel Irini offers 59 guestrooms, each equipped with a private bath and private balcony. Most rooms at the hotel look out over the water.

Amenities offered at the Hotel Irini include an onsite restaurant, snack bar and conference room. There is also a TV room as well as a laundry service at the hotel as well.